The project, which will be carried out between Irvington and Peatworks, will add to the £5 million that has already been invested by Transport Scotland across the region’s trunk road network over the last 12 months.
And Scotland TranServ say there will be a total road closure in both directions from 7 pm next Friday evening to 6 am on the Monday morning to ensure road users and workers are safe.
Scotland TranServ contract director Gordon Wilson said: “Dumfries and Galloway is the gateway to Scotland and is the first stop for thousands of tourists heading to the south west region.
“We are doing everything we can to minimise disruption by carrying these works out over one weekend, however we would advise motorists to plan ahead and leave plenty of time for their journeys.”
Local diversions will be in place throughout the duration of the works. Westbound traffic will exit the A75 at Gretna at the junction with the B721 and will pass through Rigg, Eastriggs, Dornock and Annan East roundabout before continuing onto the B6357 to rejoin the A75.
And eastbound traffic will exit onto the B6357, continue to the roundabout junction with the B721, through Dornock, Eastriggs and Rigg and rejoin the A75 at Gretna.
Motorists can also keep up-to-date with traffic information at www.trafficscotland.org or @TrafficScotland on Twitter.