She was mum and midwife Helen Renton, 44, from Dumfries – pictured above.
She was riding eastwards on her black Trek bike when she was involved in the fatal crash with a white Peugeot van travelling in the other direction at Southwick Bridge about 1.05 pm on Sunday.
Emergency services attended but Helen, who had worked at Dumfries and Galloway Royal Infirmary since last year, was pronounced dead at the scene.
She leaves a husband and young son, as well as two older children.
The driver and passenger from the van were both uninjured.
The road was closed for approximately nine hours for collision investigations to be carried out at the scene.
Appealing for witnesses, Sergeant Leigh McCulloch, from Police Scotland’s Road Policing Unit based in Lockerbie, said: “Tragically as a result of this crash the cyclist has lost her life and our thoughts at this time are with her family and friends.
“Several people stopped to help at the scene and our inquiries continue to establish what happened. I’d ask anyone who saw the crash to get in touch with officers as a priority to help our investigation.
“I’d ask anyone who was recording with dash cam on the A710 who may have captured either the van or bicycle prior to the crash, to check their systems and provide officers with any relevant footage as soon as possible.”
Those with information should report this to Police Scotland on 101 and quote incident number 1688 of 11 April 2021.
Meanwhile, one of her closest friends has launched a GoFundMe crowdfunder to help pay for funeral costs and to support her grieving family.
Paying tribute to Helen, organiser Suzi Sheerin said: “Helen simply loved life! She is a mother, daughter, midwife, friend and cycling fanatic! Her passion for cycling whilst raising money for charity was simply awe inspiring. She is loved by many and will be so sadly missed.”