The 25-year-old, whose family live in Langholm, will contest the T12 200m race at the Queen Elizabeth Olympic Park on Sunday.
And the Paralympic event, which incorporates the final leg of the IPC Grand Prix Series, in which Clegg has already tasted victory, will also feature sprint runner Jonnie Peacock, wheelchair racers David Weir and Shelly Woods and double leg amputee Richard Whitehead.
Clegg, who scooped gold at the Commonwealth Games, will be joined once again by guide runner Mikail Huggins for the race.
The Great Britain star, who also won a silver medal at the 2012 Paralympic Games, lives with a deteriorating eye condition known as Stargardt’s Macular Dystrophy, which gives her only slight peripheral vision in her left eye and means she is registered blind.
Libby limbers up for Olympic Park race
PARALYMPIC runner Libby Clegg will compete in the Sainsbury's Anniversary Games this weekend.
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