And a warning has been given of significant disruption to local people, business and motorists, with additional road closures likely.
Westlakes Demolition has revealed that approval to deconstruct 80 English Street, the former Treasure Cave bed and suite store, has been given by Dumfries and Galloway Council.
Works are expected to take three weeks to complete.
In a statement, Westlakes Demolition said: “Our machinery is now in place with more on the way ready for the go ahead to start emergency works at Dumfries.
“Our specialist demolition operatives will be working day and night to try and get the roads back open for the local businesses.”
An emergency road closure was placed on the road on April 22 due to the unsafe building, with diversions put in place.
Dumfries and Galloway Council have been in regular contact with the owner ‘over an extended period of time’ to encourage them to take action on the condition of their building.
Yesterday, a spokesman for the local authority said: “As per the Building (Scotland) Act 2003, before any demolition work can be carried out on a dangerous building, the council requires the submission of technical and safety statements from the owner for review and agreement. We have now received this necessary documentation from the owner.
“Officers from Dumfries and Galloway Council met with the owner’s demolition contractor, Westlakes Demolition, on Tuesday so the company could provide our officers with information about their process for the proposed demolition.
“If all requirements are met by the owner and the demolition company over the next few days, the contractor’s anticipated start date for the demolition is Monday May 16.
“The demolition of this building will cause disruption to local residents, businesses and motorists.
“The safety of members of the public is our paramount concern. Our officers are assessing what road closures will need to be made for this demolition to take place safely.
“Once confirmed, we will provide businesses and residents with information on the road closures at our earliest opportunity.
“Information will also be provided to the public. The demolition will not begin until the necessary road closures are in place.
“Our officers will continue to speak with the owner about the building so this situation is addressed as a matter of urgency.”