The bad weather branded by headline writers as the ‘Beast from the East’ is predicted to impact on large parts of the British Isles with heavy snow and freezing temperatures.
And the region looks set to be in the path of much of adverse weather.
The Met Office has issued a number of regional warnings as have other agencies.
Meanwhile, utilities such as Scottish Power have engineers on stand-by in case there are electricity supply problems and Transport Scotland and the local authority are on alert for any disruption on the national and local roads networks.
Forecasters say that on Tuesday there may be snow accompanied by very low temperatures in south west Scotland.
The heaviest, more persistent snow, looks likely to cross the region on Tuesday morning with further showers in places expected on Wednesday.
Residents are urged to keep a close eye on weather forecast updates, particularly on Thursday, as the snow showers are expected to continue until at least the weekend.
There is the potential for significant accumulations, warn forecasters.
Police in Dumfries and Galloway have urged drivers to take extreme care and carry emergency supplies, particularly should conditions deteriorate later in the week.