He was chosen by local party members and is set to challenge sitting MP Richard Arkless, a Stranraer-based lawyer and businessman, who is defending the seat for the SNP.
Mr Jack, 53, was born in Dumfries, attended Dalbeattie Primary School and lives at Courance, near Lockerbie.
He said: “As someone who grew up here I am very proud to be standing in my home area.
“This is a wonderful part of Scotland where my family have lived for many generations and I am very much looking forward to speaking to voters across the region.”
He stated that speaking up for rural communities was a priority and using his business experience he would push for greater investment and opportunities in the area.
Mr Jack said: “I am firmly opposed to any plans for a second independence referendum and the overwhelming majority who voted No in Dumfries and Galloway in 2014 should be respected.”
He added: “I want to see us link more closely with our neighbours in Carlisle in order to drive employment to this region and as someone with strong farming links I will always fight for rural interests.”
The Dumfries and Galloway Westminster constituency includes parts of Dumfries town and extends west to Stranraer.